This report provides an overview of the progress made in implementing activities under the Nairobi work programme on impacts, vulnerability and adaptation to climate change since the thirty-ninth session of the Subsidiary Body for Scientific and Technological Advice. It describes the continued engagement of Parties, organizations, institutions, experts, communities of practice and the private sector under the Nairobi work programme, and highlights examples of the collaborative activities between Nairobi work programme partner organizations, Parties and relevant organizations that are currently being carried out. It concludes with a brief overview of the mandated next steps.