This paper presents a synthesis of information relating to regional synergy in the context of adaptation to climate change, that could be useful in the preparation and implementation of national adaptation programmes of action (NAPAs). The paper reviews NAPA proposals as well as other relevant documents. It also describes relevant existing programmes and projects undertaken by various international entities, with the aim of identifiying opportunities for cooperative action during the NAPA process. The paper identifies possible action by which the Least Developed Countries Expert Group can enhance the promotion of regional synergy during the preparation and implementation of NAPAs