This report provides an overview of the progress made in implementing activities under the Nairobi work programme on impacts, vulnerability and adaptation to climate change. It also provides an overview of activities since the forty-third session of the Subsidiary Body for Scientific and Technological Advice and includes possible areas of future work resulting from those activities. It describes the core functions and features of the work programme and the continued engagement of Parties, partner organizations, regional centres and networks, experts and communities of practice in the implementation of activities thereunder, as well as highlighting collaborative activities undertaken with the Adaptation Committee and the Least Developed Countries Expert Group. It concludes with a brief overview of next steps.