This report summarizes the work of the Nairobi work programme on impacts, vulnerability and adaptation to climate change (NWP) between May 2016 and April 2018. This report is intended to inform the review of the NWP at the forty-eighth session of the Subsidiary Body for Scientific and Technological Advice. It describes the progress of the NWP as a ‘knowledge-for-adaptation action’ hub with over 350 partner organizations. In addition, it details specific activities that engaged diverse stakeholders in curating and disseminating actionable knowledge on climate adaptation. The NWP, through these activities, provided technical support to Parties and the constituted bodies under the Convention, identified priority knowledge gaps at the subregional level, synthesized knowledge in key thematic areas identified by Parties (e.g. human settlements, health, ecosystems and water resources, economic diversification, and indicators of climate adaptation and resilience) and fostered knowledge-sharing and learning through diverse forums and online platforms.