This report provides an overview of the progress made in implementing activities under the Nairobi work programme on impacts, vulnerability and adaptation to climate change since the forty-first session of the Subsidiary Body for Scientific and Technological Advice. It describes the continued engagement of Parties, partner organizations, regional centres and networks, experts and communities of practice in implementation of activities under the Nairobi work programme, and highlights collaborative activities with the Adaptation Committee and the Least Developed Countries Expert Group. It concludes with a brief overview of the mandated next steps